High Genetic Diversity of Measles Virus, World Health Organization European Region, 2005–2006

نویسندگان

  • Jacques R. Kremer
  • Kevin E. Brown
  • Li Jin
  • Sabine Santibanez
  • Sergey V. Shulga
  • Yair Aboudy
  • Irina V. Demchyshyna
  • Sultana Djemileva
  • Juan E. Echevarria
  • David F. Featherstone
  • Mirsada Hukic
  • Kari Johansen
  • Bogumila Litwinska
  • Elena Lopareva
  • Emilia Lupulescu
  • Andreas Mentis
  • Zefira Mihneva
  • Maria M. Mosquera
  • Mark Muscat
  • M.A. Naumova
  • Jasminka Nedeljkovic
  • Ljubov S. Nekrasova
  • Fabio Magurano
  • Claudia Fortuna
  • Helena Rebelo de Andrade
  • Jean-Luc Richard
  • Alma Robo
  • Paul A. Rota
  • Elena O. Samoilovich
  • Inna Sarv
  • Galina V. Semeiko
  • Nazim Shugayev
  • Elmira S. Utegenova
  • Rob van Binnendijk
  • Lasse Vinner
  • Diane Waku-Kouomou
  • T. Fabian Wild
  • David W.G. Brown
  • Annette Mankertz
  • Claude P. Muller
  • Mick N. Mulders
چکیده

During 2005-2006, nine measles virus (MV) genotypes were identified throughout the World Health Organization European Region. All major epidemics were associated with genotypes D4, D6, and B3. Other genotypes (B2, D5, D8, D9, G2, and H1) were only found in limited numbers of cases after importation from other continents. The genetic diversity of endemic D6 strains was low; genotypes C2 and D7, circulating in Europe until recent years, were no longer identified. The transmission chains of several indigenous MV strains may thus have been interrupted by enhanced vaccination. However, multiple importations from Africa and Asia and virus introduction into highly mobile and unvaccinated communities caused a massive spread of D4 and B3 strains throughout much of the region. Thus, despite the reduction of endemic MV circulation, importation of MV from other continents caused prolonged circulation and large outbreaks after their introduction into unvaccinated and highly mobile communities.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Molecular genotyping and epidemiology of measles virus transmission in the World Health Organization European Region, 2007-2009.

BACKGROUND In 2002, the World Health Organization (WHO) adopted a goal to eliminate measles in the European Region by 2010. Measles elimination is defined as the interruption of indigenous measles virus (MV) transmission. The molecular epidemiology of MV transmission in the WHO European Region was studied through the investigation of reported cases and outbreaks to monitor the region's progress...

متن کامل

Toward rubella elimination in Poland: need for supplemental immunization activities, enhanced surveillance, and further integration with measles elimination efforts.

BACKGROUND All Member States of the World Health Organization (WHO) European Region have endorsed rubella elimination and congenital rubella syndrome (CRS) prevention. However, Poland has continued high levels of reported rubella. METHODS We reviewed rubella incidence in Poland since 1966 and analyzed national aggregated surveillance data from the period 2003-2008 and case-based data from 4 p...

متن کامل

Progress toward measles elimination--European Region, 2005--2008.

In 2002, the World Health Organization (WHO) Regional Committee for the European Region (EUR) revised earlier targets to eliminate indigenous measles and achieve rubella control by resolving to 1) eliminate both diseases in EUR member states by 2010, using a combination of routine and supplementary immunization strategies, and 2) monitor progress toward this goal through improved surveillance. ...

متن کامل

[The State of Measles and Rubella in the WHO European region].

The long-standing and widespread use of vaccines against measles has resulted in a dramatic decline in cases and measles mortality worldwide compared with the pre-vaccination era.All regions of the World Health Organization (WHO) have measles elimination goals and the WHO regions of the Americas, Europe and Western Pacific also have rubella elimination goals. This article aims to report on prog...

متن کامل

Measles still spreads in Europe: who is responsible for the failure to vaccinate?

All countries in the European Region of the World Health Organization (WHO) have renewed their commitment to eliminate measles transmission by 2015. Measles elimination is a feasible target but requires vaccination coverage above 95% with two doses of a measles-mumps-rubella vaccine (MMR) in all population groups and in all geographical areas. Measles has re-emerged in the EU recently, due to s...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Emerging Infectious Diseases

دوره 14  شماره 

صفحات  -

تاریخ انتشار 2008